Cryogenic LNG hoses is mainly used for LNG unloading interconnection between transport ships, in the process of LNG can quickly continuously the effective transmission. The FLNG transmission performance of cryogenic LNG hoses is vital role for the economy and safety of marine oil and gas development. Therefore, the detailed investigation and analysis characteristics for internal flow in cryogenic LNG hoses has important guiding significance for practical engineering design. In the work, computational fluid dynamics (CFD) is employed to build the numerical model of the internal flow field with corrugated structure inside LNG hose. Structural and process parametric studies are performed to investigate the effects of the pressure, velocity, temperature and heat transfer coefficient of the internal flow, and also the results from this model is verified against the existing experimental results. Moreover, the dimensionless correction coefficient of heat transfer and pressure-drop are obtained for the internal flow characteristics in cryogenic LNG hose. The results of this research provide a helpful support to the design of cryogenic LNG hose, and also provide some useful reference to the design of FLNG unloading process.