With the development of sturgeon farming in the country, we can expect the occurrence and increase of various infectious diseases in farms, and in this regard, the use of specific probiotics (Weissella confusa and Lactococcus lactis) are important in promoting the health of these fish. In this research, which was conducted at the Iranian sturgeon research institute (Guilan-Rasht), a total of 500 pieces of Siberian sturgeon were randomly introduced in 12 fiberglass tubs with a total volume of 500 liters and a dewatering volume of 300 liters. The fish had an average weight of 84.08 ±3.12 g. This study with 3 experimental treatments (each treatment with three replications) including 150 mg (treatment 1), 300 mg (treatment 2) and 450 mg (treatment 3) specific probiotics per kg of food and a group The control (basal diet without probiotic bacteria) was performed for 10 weeks. The effect of adding two probiotic strains (Weissella confusa and Lactococcus lactis) isolated from the intestine of Siberian sturgeon on growth indices, Liver enzymes, Immune markers were determined. The results of this study showed that by adding native and specific probiotics in different concentrations to the diet, a significant difference was observed in the feed conversion ratio (p <0.05). There was no significant difference between daily growth, specific growth rate, body weight gain and obesity coefficient between treatments and the control group (p> 0.05). The highest and lowest values ​​of immunoglobulin M and lysozyme were observed with significant differences in treatments 1 and 3, respectively (p <0.05). Based on the results of this study, it can be stated that the optimal concentration of specific probiotics used in the diet of Siberian sturgeon to improve growth and safety indices is equivalent to 300 mg / kg of feed.
 

Siberian Sturgeon, Specific Probiotics, Growth Indices, Immune